Sermorelin 5mg


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Sermorelin is a human growth hormone-releasing hormone (GHRH or GRF) used for diagnostic evaluation

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What Is Sermorelin ?

Sermorelin is a human growth hormone-releasing hormone (GHRH or GRF) used for diagnostic evaluation of pituitary function and also for increasing growth in children. Off label usage of sermorelin may include acute or age-related growth hormone insufficiency. Sermorelin is discontinued; generic versions may be available.

Sermorelin acts on the growth hormone releasing hormone receptor (GHRHr) in the pituitary to regulate cellular activities. GHRHr is the natural receptor for the endogenous hormone, GHRH, and for sermorelin. This receptor regulates growth hormone release directly by stimulation and indirectly by a feedback relationships with somatostatin.

Sermorelin Peptide and Cognition

In the early 2000s, clinical research studies were conducted with 89 older subjects between 68 and 69 years of age, to explore the correlation (if any) between tapering growth hormone release and impaired cognition. Scientists consider that with increasing age, levels of growth hormone naturally decline, which result in reduced physiological functions, including cognition (i.e. ability to collect, process and recollect information). Following the introduction of Sermorelin, it was observed that there was an apparent improved performance in the Wechsler Adult Intelligence scale (WAIS) – i.e. improved IQ levels, picture arrangement tests and verbal tests – amongst the test subjects.

Biochemical properties

Sermorelin possesses several notable biochemical properties that contribute to its physiological effects. These include its resistance to enzymatic degradation, stability, and selectivity towards the GHRH receptor. Understanding these properties is crucial for optimizing its pharmaceutical formulation and clinical use.

Our laboratory is committed to providing high quality, reliable products to support the advancement of scientific research. If you have any questions or special requirements, please don’t hesitate to contact us.

Potential side effects and drug interactions

Side effects

The most common side effect of sermorelin is caused by its injection under your skin. You may experience any of the following at the site of injection:

  • irritation
  • itching
  • sensitivity
  • swelling
  • pain
  • redness

These reactions are typically short-lived and disappear without any action. As you get better at self-administering the shots, these symptoms may stop for good.


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